‌A comparative study between citanest and mepivacaine ‌‌on high blood pressure in hypertensive patients

‌A comparative study between citanest and mepivacaine ‌‌on high blood pressure in hypertensive patients Dr. SM. Ghoreyshian * - Dr. A. Teymouri** - Dr. M. Mansouri** *- Assistant professor of Oral Maxillofacial Surgery Dept.- Faculty of Dentistry- Isfahan University of Medical Sciences. ** - Dentist.  Background and aim: Selection the proper local anestheteic drug in dental procedures especially for patients with cardiovascular problems is very important. Recently, a lot of studies have been conducted on local anesthetic drugs such as mepivacaine, prilocain eand particularly lidocaine but much attention has not been paid to homodynamic effects of prilocaine associated with citanest as a vasoconstrictor that are recommended for cardiovascular patients. The aim of the present study was to compare the effects of citanest and mepivacaine on blood pressure of hypertensive patients. Materials and Methods: In this clinical study,18 hypertensive patients (15 females, 3 males), referred to Isfahan dental faculty, with the mean age of 49.7, who needed extraction or mandibular surgery, were selected. Mepivacaine was injected in one session and citanest in later session. The injection was interior alveolar nerve block for all patients. Each patient,s blood pressure and pulse rate were measured durnig, after 5 and 10 minutes of injection. Data were collected and analyzed by SPSS - 4 software and repeated measure analysis test. Results: Average pulse rate and blood pressure (systolic and diastolic) after 5 minutes for citanest 0.77±2.81,0.36±1.34 and 3.3±0.7, respectively and 10 minutes were 0.55±3.11,0.24±1.39 and, were 0.23±1.55, respectively For mepivacaine after 5 minutes these figures were in order 0.77±5.2,0.5±0.9 and 0.12±0.48 and after ten minutes were in order 0/88±5.29,0.3±1.03 and 0.17±0.54. No statistically significant diffrernce was found between two drugsin all cases. Conclusion: The findings of this study show that two local anesthetic drugs: citanest with vaso constriction and mepivacaine without vasoconstriction in cardiovascular patients affected with hypertension have equal effects in dentistry procedures. Key Words: Hypertension - Citanest – Mepivacaine- Local anesthesia - Cardiovascular patients.